cobicistat will improve the level or outcome of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. A diminished dose of diazepam can be expectedLonafarnib may raise the AUC and peak focus of CYP2C19 substrates. If coadministration unavoidable, observe for adverse reactions and lessen the CYP2C19 subs